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Long Term Multiview Imaging for Large, Living Samples with Light Sheet Microscopy

Imagine you had access to an imaging system that could perform fluorescence imaging on large, living samples, with virtually no phototoxicity or bleaching and with high temporal resolution.

That is exactly what Lightsheet Z.1 from Carl Zeiss does. The unique Multiview Light Sheet Fluorescence Microscope allows you to record the development of large, living samples and gently image them to deliver exceptionally high information content.

It is also fast. Lightsheet Z.1 gives you the tools you need to work at unprecedented speed and acquire images of your whole sample volume at sub-cellular resolution – in a fraction of the time it takes using other techniques.


Multiview Imaging. Delivering true flexibility


The best of all worlds. Optimized light sheet microscopy optics


Fluorescent imaging for large living samples

Perform previously impossible experiments
Because Lightsheet Z.1 is the gentlest way to observe the development of living specimens, it opens up a new world of experiments for your research. These are just some of the light sheet microscopy applications that are now available to you.

Morphogenesis and embryogenesis
Perform fluorescence imaging of spatio-temporal patterns within cells during embryogenesis of model organisms such as zebrafish and Drosophila melanogaster.

Organogenesis and cell dynamics
Fast imaging of cellular dynamics in embryos and small organisms like cell migration, cardiac development, blood flow, vascular development, neuro-development or calcium imaging.

3D cell cultures
Benefit from live imaging of 3D cell cultures, spheroids and cysts, tissue and organotypic cultures. Use your images to analyse cell migration, expression patterns and cell proliferation.

Imaging of marine organisms
Use Lightsheet Z.1 for fluorescence imaging of marine organisms such as ciona, squid, plankton and flatworms.

Structural features of fluorescently labeled living specimens
Acquire detailed volume imaging of fixed and living specimens, for example zebrafish and Medaka fish.


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